E Head

Butterfield, D. ., Barone, E. ., Di Domenico, F. ., Cenini, G. ., Sultana, R. ., Murphy, M. ., … Head, E. . (2012). Atorvastatin treatment in a dog preclinical model of Alzheimer’s disease leads to up-regulation of haem oxygenase-1 and is associated with reduced oxidative stress in brain. The International Journal of Neuropsychopharmacology, 15(7), 981-7. https://doi.org/10.1017/S1461145711001118

Di Domenico, F. ., Pupo, G. ., Tramutola, A. ., Giorgi, A. ., Schininà, M. ., Coccia, R. ., … Perluigi, M. . (2014). Redox proteomics analysis of HNE-modified proteins in Down syndrome brain: clues for understanding the development of Alzheimer disease. Free Radical Biology & Medicine, 71, 270-280. https://doi.org/10.1016/j.freeradbiomed.2014.03.027

Perluigi, M. ., Pupo, G. ., Tramutola, A. ., Cini, C. ., Coccia, R. ., Barone, E. ., … Di Domenico, F. . (2014). Neuropathological role of PI3K/Akt/mTOR axis in Down syndrome brain. Biochimica Et Biophysica Acta, 1842(7), 1144-53. https://doi.org/10.1016/j.bbadis.2014.04.007

Cenini, G. ., Fiorini, A. ., Sultana, R. ., Perluigi, M. ., Cai, J. ., Klein, J. ., … Butterfield, D. . (2014). An investigation of the molecular mechanisms engaged before and after the development of Alzheimer disease neuropathology in Down syndrome: a proteomics approach. Free Radical Biology & Medicine, 76, 89-95. https://doi.org/10.1016/j.freeradbiomed.2014.08.006

Butterfield, D. ., Di Domenico, F. ., Swomley, A. ., Head, E. ., & Perluigi, M. . (2014). Redox proteomics analysis to decipher the neurobiology of Alzheimer-like neurodegeneration: overlaps in Down’s syndrome and Alzheimer’s disease brain. The Biochemical Journal, 463(2), 177-89. https://doi.org/10.1042/BJ20140772 (Original work published 2014)

Di Domenico, F. ., Pupo, G. ., Mancuso, C. ., Barone, E. ., Paolini, F. ., Arena, A. ., … Perluigi, M. . Bach1 overexpression in Down syndrome correlates with the alteration of the HO-1/BVR-a system: insights for transition to Alzheimer’s disease. Journal of Alzheimer’s Disease : JAD, 44(4), 1107-20. https://doi.org/10.3233/JAD-141254 (Original work published 2015)

Triani, F. ., Tramutola, A. ., Di Domenico, F. ., Sharma, N. ., Butterfield, D. ., Head, E. ., … Barone, E. . (2018). Biliverdin reductase-A impairment links brain insulin resistance with increased Aβ production in an animal model of aging: Implications for Alzheimer disease. Biochimica Et Biophysica Acta. Molecular Basis of Disease, 1864(10), 3181-3194. https://doi.org/10.1016/j.bbadis.2018.07.005

Barone, E. ., Cenini, G. ., Di Domenico, F. ., Martin, S. ., Sultana, R. ., Mancuso, C. ., … Butterfield, D. . (2011). Long-term high-dose atorvastatin decreases brain oxidative and nitrosative stress in a preclinical model of Alzheimer disease: a novel mechanism of action. Pharmacological Research, 63(3), 172-80. https://doi.org/10.1016/j.phrs.2010.12.007

Martin, S. ., Cenini, G. ., Barone, E. ., Dowling, A. ., Mancuso, C. ., Butterfield, D. ., … Head, E. . (2011). Coenzyme Q10 and cognition in atorvastatin treated dogs. Neuroscience Letters, 501(2), 92-5. https://doi.org/10.1016/j.neulet.2011.06.054 (Original work published 2011)