An Aspartyl Cathepsin Targeted PET Agent: Application in an Alzheimer's Disease Mouse Model.
| Author | |
|---|---|
| Abstract |
:
Early detection of Alzheimer's disease (AD) pathology is a serious challenge for both diagnosis and clinical trials. The aspartyl protease, Cathepsin D (CatD), is overexpressed in AD and could be a biomarker of disease. We have previously designed a unique contrast agent (CA) for dual-optical and magnetic resonance imaging of the activity of the CatD class of enzymes. |
| Year of Publication |
:
0
|
| Journal |
:
Journal of Alzheimer's disease : JAD
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| Volume |
:
61
|
| Issue |
:
3
|
| Number of Pages |
:
1241-1252
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| Date Published |
:
2018
|
| ISSN Number |
:
1387-2877
|
| URL |
:
https://content.iospress.com/openurl?genre=article&id=doi:10.3233/JAD-170115
|
| DOI |
:
10.3233/JAD-170115
|
| Short Title |
:
J Alzheimers Dis
|
| Download citation |
