Acanthoic acid suppresses lipin1/2 via TLR4 and IRAK4 signalling pathways in EtOH- and lipopolysaccharide-induced hepatic lipogenesis.

Author
:
J Song
X Han
YL Yao
YM Li
J Zhang
DY Shao
LS Hou
Y Fan
SZ Song
LH Lian
JX Nan
YL Wu
Abstract
:

In alcoholic liver disease, alcohol and lipopolysaccharide (LPS) are major stimulation factors of hepatic lipogenesis. Our objective was to determine the protective mechanism of acanthoic acid (AA) in EtOH- and LPS-induced hepatic lipogenesis.
Year of Publication
:
2018
Journal
:
The Journal of pharmacy and pharmacology
Date Published
:
2018
ISSN Number
:
0022-3573
URL
:
http://dx.doi.org/10.1111/jphp.12877
DOI
:
10.1111/jphp.12877
Short Title
:
J Pharm Pharmacol
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