A mutational signature associated with alcohol consumption and prognostically significantly mutated driver genes in esophageal squamous cell carcinoma.

Author
:
XC Li
MY Wang
M Yang
HJ Dai
BF Zhang
W Wang
XL Chu
X Wang
H Zheng
RF Niu
W Zhang
KX Chen
Abstract
:

Esophageal squamous cell carcinoma (ESCC) is often diagnosed at an advanced and incurable stage. Information on driver genes and prognosticators in ESCC remains incomplete. The objective was to elucidate significantly mutated genes (SMGs), mutational signatures, and prognosticators in ESCC.
Year of Publication
:
2018
Journal
:
Annals of oncology : official journal of the European Society for Medical Oncology
Date Published
:
2018
ISSN Number
:
0923-7534
URL
:
https://academic.oup.com/annonc/article-lookup/doi/10.1093/annonc/mdy011
DOI
:
10.1093/annonc/mdy011
Short Title
:
Ann Oncol
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