Variability Assessment of 90 Salivary Proteins in Intra-Day and Inter-Day Samples from Healthy Donors by Multiple Reaction Monitoring-Mass Spectrometry.

Saliva is an attractive sample source for the biomarker-based testing of several diseases, especially oral cancer. Here, we sought to apply multiplexed LC-MRM-MS to precisely quantify 90 disease-related proteins and assess their intra- and inter-individual variability in saliva samples from healthy donors.